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Recent advances in cancer immunology and immunology-based anticancer therapies

Sunil Kumar1, Reena Vohra Saini2, Neeraj Mahindroo3

  • 1School of Pharmaceutical Sciences, Shoolini University, Post Box 9, Solan, 173212, Himachal Pradesh, India.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|December 5, 2017
PubMed

Cancer immunotherapies offer promise for cure of cancer with specificity and minimal toxicity. Recent developments in cancer immunology have led to the better understanding of role of immune regulatory mechanisms in cancer. There is rapid progress in this field in the last few years. Several clinical studies report the efficacy of immunotherapies for treating cancer. The immunology-based anticancer therapies have shown better safety profiles in clinic as compared to other chemotherapeutic agents, thus increasing interest in this area. This review summarizes recent advances in cancer immunology and discusses tumor microenvironment and immunology-based anticancer therapies, including vaccines and therapies targeting immune checkpoints.

Keywords:
CytokinesImmune checkpointsImmune oncologyImmunotherapyTh1/Th2

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