Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Selectins01:25

Selectins

4.4K
Cell adhesion is  an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient cell interactions occur between cells of different tissue types, such as between neutrophils and endothelial cells. Selectins are one class of cell adhesion molecules (CAMs) that bind carbohydrate ligands to form transient cell adhesion. They are rod-like proteins with a long extracellular part of variable length ending with the lectin domain,...
4.4K
Immunoglobulin-like Cell Adhesion Molecules01:31

Immunoglobulin-like Cell Adhesion Molecules

4.4K
Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
4.4K
Complement System01:27

Complement System

11.0K
The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a...
11.0K
Cell Adhesion Molecules - Types and Functions01:20

Cell Adhesion Molecules - Types and Functions

9.9K
Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
CAM Families
The Integrin family of proteins is primarily  involved...
9.9K
Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

9.6K
The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
9.6K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

84.4K
Overview
84.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experimental evolution to thermal stress indicates climate resilience in a cosmopolitan arthropod.

eLife·2026
Same author

A curated global dataset of naturally occurring aphid-fungal associations.

Scientific data·2026
Same author

An SMC-domain protein regulates eupyrene spermiogenesis and sperm migration in a cosmopolitan insect, Plutella xylostella.

Journal of insect physiology·2026
Same author

PDK1-mediated PI3K/Akt signaling regulates metabolic and developmental programs in a cosmopolitan pest.

Pest management science·2026
Same author

Bioactivity and mitochondrial mode of action of methyl benzoate against the tea pest Ectropis grisescens.

Pesticide biochemistry and physiology·2026
Same author

Fully computational design of PAM-relaxed <i>Staphylococcus aureus</i> Cas9 with expanded targeting capability using UniDesign.

eLife·2026
Same journal

Characterization of interleukin-20 from black carp and its role in the antiviral innate immunity.

Developmental and comparative immunology·2026
Same journal

The spatiotemporal immune response patterns of Gryllus bimaculatus to infection by the bioinsecticide Metarhizium anisopliae.

Developmental and comparative immunology·2026
Same journal

Characterization and determination of the immunomodulatory activity of intestinal microbiota microorganisms isolated from free-range Cornu aspersum snails in olive groves before and after aestivation.

Developmental and comparative immunology·2026
Same journal

Comprehensive analysis of pathogenic mechanisms of Enterobacter cancerogenus ECL9 in silkworms.

Developmental and comparative immunology·2026
Same journal

Isolate-Dependent Pathogenicity and Host-Pathogen Interactions of Toxigenic Penicillium roqueforti in the Galleria mellonella Model.

Developmental and comparative immunology·2026
Same journal

PPARγ mediates selenomethionine-induced suppression of NF-κB signaling in bovine endometrial epithelial cells.

Developmental and comparative immunology·2026
See all related articles

Related Experiment Video

Updated: Feb 17, 2026

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
11:44

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo

Published on: September 18, 2014

9.3K

Insect C-type lectins in innate immunity.

Xiaofeng Xia1, Minsheng You1, Xiang-Jun Rao2

  • 1State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Institute of Applied Ecology, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Key Laboratory of Integrated Pest Management for Fujian-Taiwan Crops, Ministry of Agriculture, Fuzhou 350002, China; Key Laboratory of Green Control of Insect Pests (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou 350002, China; Fujian-Taiwan Joint Centre for Ecological Control of Crop Pests, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

Developmental and Comparative Immunology
|December 5, 2017
PubMed
Summary
This summary is machine-generated.

C-type lectins (CTLs) are calcium-dependent proteins crucial for insect immunity. This review summarizes insect CTLs, comparing them to vertebrate counterparts and detailing their roles in innate immunity.

Keywords:
Carbohydrate-recognition domainImmune responseLectinsLepidopteraPattern recognition

More Related Videos

Automated Separation of C. elegans Variably Colonized by a Bacterial Pathogen
11:18

Automated Separation of C. elegans Variably Colonized by a Bacterial Pathogen

Published on: March 21, 2014

9.0K
Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals
06:55

Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals

Published on: January 18, 2016

10.4K

Related Experiment Videos

Last Updated: Feb 17, 2026

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
11:44

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo

Published on: September 18, 2014

9.3K
Automated Separation of C. elegans Variably Colonized by a Bacterial Pathogen
11:18

Automated Separation of C. elegans Variably Colonized by a Bacterial Pathogen

Published on: March 21, 2014

9.0K
Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals
06:55

Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals

Published on: January 18, 2016

10.4K

Area of Science:

  • Immunology
  • Biochemistry
  • Entomology

Background:

  • C-type lectins (CTLs) are proteins characterized by carbohydrate-recognition domains (CRDs).
  • They bind ligands in a calcium-dependent manner and are vital in animal immune responses.
  • In insects, CTLs mediate various innate immune functions, including opsonization and pathogen recognition.

Purpose of the Study:

  • To review insect C-type lectins.
  • To compare insect CTLs with their vertebrate homologs.
  • To focus on the domain organization and innate immune functions of insect CTLs.

Main Methods:

  • Literature review and comparative analysis.
  • Summarization of existing research on insect CTLs.
  • Focus on domain organization and functional roles.

Main Results:

  • Insect CTLs share functional similarities with vertebrate CTLs but exhibit distinct domain organizations.
  • CTLs are involved in diverse innate immune processes in insects, such as pathogen clearance and immune homeostasis.
  • Specific examples of insect CTLs and their functions are discussed.

Conclusions:

  • Insect CTLs represent a conserved yet diverse family of immune proteins.
  • Understanding insect CTLs provides insights into invertebrate innate immunity.
  • Further research into CTL structure-function relationships can reveal novel immune mechanisms.