[Expression of receptor activator of nuclear factor-κB ligand in keratocystic odontogenic tumor before and after decompression]
Related Experiment Video
Updated: Feb 17, 2026
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Bo Zhang1, Wen-Cheng Ye, Ying Li
1Lishui Hospital of Zhejiang University, Lishui Central Hospital. Lishui 323000, Zhejiang Province, China.
Purpose:
To investigate the expression of receptor activator of nuclear factor-κB ligand (RANKL) in keratocystic odontogenic tumor (KCOT) before and after decompression.
Methods:
Twenty two pairs of paraffin-embeded tissue specimens of KCOT were collected and subjected to immunohistochemical analysis of RANKL.The data were analyzed with SPSS17.0 software package for paired t test.
Results:
RANKL positive cells were observed in the preoperative KCOT epithelium. The expression of RANKL was down-regulated after decompression(P<0.05).
Conclusions:
Decrease of RANKL expression after decompression may facilitate the lining epithelium of KCOT transforming to normal oral mucosal epithelium.
