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Related Experiment Videos

The "neck sign" in scleroderma.

A J Barnett

    Arthritis and Rheumatism
    |February 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    The "neck sign," a skin change on neck extension, is a highly accurate diagnostic indicator for scleroderma. This sign was positive in most scleroderma patients but absent in those with Raynaud's disease or healthy controls.

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    Area of Science:

    • Rheumatology
    • Dermatology
    • Internal Medicine

    Background:

    • Scleroderma is a chronic autoimmune disease characterized by hardening and tightening of the skin.
    • Accurate and early diagnosis of scleroderma is crucial for effective management.
    • Existing diagnostic methods may have limitations in specificity or accessibility.

    Purpose of the Study:

    • To evaluate the diagnostic utility of the
    • neck sign
    • in patients with scleroderma.

    Main Methods:

    • The study observed the presence or absence of the
    • neck sign
    • in patients diagnosed with scleroderma.
    • The sign's prevalence was also assessed in patients with primary Raynaud's disease and in healthy control subjects.

    Related Experiment Videos

  • Neck skin changes were noted during head extension to elicit the sign.

    • Main Results:

    • The
    • neck sign
    • was positive in over 90% of patients with scleroderma.
    • Conversely, the sign was consistently negative in patients with primary Raynaud's disease.
    • The
    • neck sign
    • was also negative in all evaluated control subjects.

    Conclusions:

    • The
    • neck sign
    • demonstrates high sensitivity and specificity for scleroderma diagnosis.
    • This clinical finding represents a simple, non-invasive, and useful diagnostic aid for scleroderma.
    • Its absence in primary Raynaud's disease and controls further supports its utility in differentiating scleroderma.