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Does Serum lipid profile differ in anemia and non-anemic older subjects?
Mahshid Shirvani1, Mohsen Vakili Sadeghi2, Seyed Reza Hosseini3
1Student Research Committee, Babol University of Medical Sciences, Babol. Iran.
Caspian Journal of Internal Medicine
|December 5, 2017
Summary
Elderly individuals with anemia and iron deficiency anemia (IDA) exhibit lower lipid profiles, including triglyceride and cholesterol levels. Further research is recommended to understand the underlying mechanisms of this association.
Area of Science:
- Gerontology
- Hematology
- Clinical Biochemistry
Background:
- Anemia symptoms may be less pronounced in overweight/obese individuals.
- Investigating the link between anemia and lipid profiles in the elderly is important.
Purpose of the Study:
- To examine the relationship between anemia and iron deficiency anemia (IDA) and the lipid profile status in an elderly population.
Main Methods:
- A cross-sectional study using data from the Amirkola Health and Ageing Project (AHAP).
- Collected demographic data and blood samples for lipid indexes (triglyceride, cholesterol, HDL, LDL) and anemia parameters after fasting.
- Analyzed data using chi-square, t-test, and Pearson correlation (SPSS), with p<0.05 significance.
Main Results:
- Prevalence of anemia and IDA was 31% and 9% respectively in the elderly cohort.
- Mean serum triglyceride, cholesterol, and LDL levels were lower in participants with anemia and IDA compared to controls.
- HDL levels were similar across groups, but statistically significant differences were observed concerning age and obesity (P=0.001).
Conclusions:
- Elderly individuals with anemia and IDA demonstrate reduced levels of triglycerides and cholesterol.
- These findings align with some previous research, suggesting a need for further investigation into the causal mechanisms.
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