[Premature outflow tract ventricular contraction combined with complete bundle branch block: the characteristic
1Centre of Cardiology, Tianjin Medical University General Hospital, Tianjin 300052, China.
Insights
Electrocardiogram (ECG) analysis for premature ventricular contraction (PVC) in patients with complete left/right bundle branch block (CL/RBBB) can be misleading. Mapping and ablation are crucial for accurate PVC origin determination in these cases.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Diagnostics
Background:
- Bundle branch blocks (BBB) can complicate electrocardiogram (ECG) interpretation.
- Premature ventricular contractions (PVCs) originating in patients with BBB require careful analysis to determine their source.
Purpose of the Study:
- To investigate ECG characteristics of PVCs in patients with complete left or right bundle branch block (CL/RBBB).
- To identify potential ECG features for PVC origin in CL/RBBB patients.
- To compare ECG findings between patients with and without CL/RBBB.
Main Methods:
- Retrospective analysis of 8 outflow tract PVC patients with CL/RBBB undergoing radiofrequency ablation.
- Division of patients into complete right bundle branch block (CRBBB) and complete left bundle branch block (CLBBB) groups.
- Comparison of ECG characteristics and potential features with a control group without CL/RBBB.
Main Results:
- Most PVCs showed a precordial R/S>1 transition at lead V4, with exceptions in CRBBB and CLBBB groups.
- Precordial R/S>1 transition was not delayed compared to sinus rhythm in the CLBBB group.
- No significant difference in QRS duration between sinus rhythm and PVC in CL/RBBB patients, unlike the control group.
Conclusions:
- Bundle branch block can lead to misinterpretation of PVC origin on ECG during sinus rhythm.
- Accurate determination of PVC origin in CL/RBBB patients relies on electrophysiological mapping and ablation results.
Abstract:
Objective: To explore the characteristics of electrocardiogram(ECG) and target potential features of premature ventricular contraction (PVC) in patients with complete left/right bundle branch block (CL/RBBB) and compare with those without CL/RBBB. Methods: A retrospective analysis was done in 8 outflow tract PVC patients with CL/RBBB, who successfully underwent radiofrequency ablation from August 2009 to June 2017. According to the bundle branch block chamber, patients were divided into the complete right bundle branch block (CRBBB) group (n=4) and the complete left bundle branch block (CLBBB) group (n=4). The control group were those who successfully underwent ablation at the same position as the above two groups but without CL/RBBB. The characteristics of ECG and target potential features were compared among groups. Results: One case in the CRBBB group was successfully ablated in the great cardiac vein with precordial R/S>1 transition at V(1) and one case in the CLBBB group was successfully ablated in the right coronary cusp with precordial R/S>1 transition at V(2), while other 6 cases were all with precordial R/S>1 transition at lead V(4). Precordial R/S>1 transition was not later than sinus rhythm (SR) in the CLBBB group. No statistical difference was found in the QRS complex duration between SR and PVC in the CL/RBBB patients [(134.38±23.80)ms vs (156.75±25.93)ms, P>0.05], while statistical difference was shown in the control group [(92.63±5.76)ms vs (140.25±15.97)ms, P<0.05]. Conclusion: Bundle branch block can lead to misjudgment of PVC origin with CL/RBBB during sinus rhythm, thus the origin chamber of the PVC should be determined according to the mapping and ablation result.
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