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Cranioplasty Using Autoclaved Autologous Skull Bone Flaps Preserved at Ambient Temperature
Dominic Anto1, Raju Paul Manjooran1, Rajeev Aravindakshan2
1Department of Community Medicine, Pushpagiri Institute of Medical Sciences and Research Centre, Thiruvalla, Kerala, India.
Journal of Neurosciences in Rural Practice
|December 6, 2017
Summary
Autoclaved autologous bone grafts for cranioplasty (CP) show good short-term outcomes in 86% of patients. While complications like osteomyelitis and bone resorption occurred, secondary CP with titanium mesh was successful.
Area of Science:
- Neurosurgery
- Surgical Reconstruction
Background:
- Cranioplasty (CP) utilizes autologous bone or synthetic materials.
- Sterilization and preservation of autologous bone flaps remain surgeon-dependent choices.
Purpose of the Study:
- To evaluate the clinical outcomes of cranioplasty using autoclaved autologous bone grafts.
- Assess both short-term and long-term results of this reconstructive technique.
Main Methods:
- Retrospective observational study in a tertiary care neurosurgery department.
- Included 72 patients undergoing CP with autoclaved autologous skull flaps.
- Data analyzed for pre- and post-operative characteristics, with continuous variables summarized.
Main Results:
- Satisfactory primary CP outcome in 86.11% of cases.
- Complications included osteomyelitis (5.56%), bone resorption (1.39%), and fragmentation/fracture (6.94%).
- Secondary CP using titanium mesh was successful in all complication cases.
Conclusions:
- Autoclaved autologous bone flaps demonstrate efficacy and safety for cranial reconstruction.
- Further large-scale retrospective and prospective studies are needed to establish standardized guidelines for bone flap management.
