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Reversible splenial lesion syndrome (RESLES) coinciding with cerebral venous thrombosis: a report of two cases

Jingyi Liu1, Dacheng Liu1, Bo Yang1

  • 1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Therapeutic Advances in Neurological Disorders
|December 6, 2017
PubMed

A total of two postpartum women with no noteworthy medical history presented with persistent headache. Brain magnetic resonance imaging (MRI) of both revealed extensive cerebral venous thrombosis, concurrently with abnormal signals of the splenium of the corpus callosum (SCC): The splenium appeared hyperintense on T2-weighted sequences, fluid-attenuated inversion recovery (FLAIR), and diffusion-weighted imaging (DWI) imaging, and hypointense on T1 sequences and apparent diffusion coefficient (ADC) map. The patients were given thrombolytic therapy. Clinically, both patients achieved recovery with no neurologic sequelae, and follow-up MRI revealed complete resolution of the lesion in the SCC at day 36 and day 37 after initial presentation, respectively.

Keywords:
MRIRESLEScerebral venous thrombosissplenium corpus callosum

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