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Wilkie's syndrome.

Renato Farina1, Pietro Valerio Foti1, Giuseppe Cocuzza1

  • 1Radiodiagnostic and Radiotherapy, University Hospital "Policlinico-Vittorio Emanuele", Via Santa Sofia 78, 95123 Catania, Italy.

Journal of Ultrasound
|December 6, 2017
PubMed
Summary
This summary is machine-generated.

Superior mesenteric artery syndrome (Wilkie's syndrome) is a vascular condition caused by a narrow aorto-mesenteric angle. A high-calorie diet successfully treated a patient by restoring the angle and resolving symptoms.

Keywords:
Superior mesenteric arteryUltrasoundWilkie’s syndrome

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Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Radiology

Background:

  • Superior mesenteric artery syndrome (SMAS), or Wilkie's syndrome, is a rare vascular condition.
  • It results from an abnormally narrow angle (<22°) between the superior mesenteric artery and the aorta.
  • This compression can affect the duodenum and left renal vein, causing symptoms like abdominal pain, vomiting, and varicocele.

Observation:

  • A female patient presented with significant weight loss (12 kg in 4 months) and recurrent postprandial vomiting.
  • B-mode ultrasound revealed a reduced aorto-mesenteric angle, consistent with Wilkie's syndrome.
  • The patient's symptoms were attributed to acquired SMAS, likely due to reduced perivascular fat from rapid weight loss.

Findings:

  • Diagnosis of Wilkie's syndrome was confirmed through ultrasound imaging.
  • The patient was treated with a high-calorie diet.
  • Follow-up ultrasound demonstrated a restored aorto-mesenteric angle due to increased perivascular fat, with complete symptom resolution.

Implications:

  • This case highlights the effectiveness of nutritional intervention in managing acquired Superior Mesenteric Artery Syndrome.
  • Restoration of perivascular fat through dietary changes can reverse the vascular compression.
  • Early diagnosis and appropriate management can lead to favorable patient outcomes in Wilkie's syndrome.