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In vivo selection of a multidrug-resistant Aeromonas salmonicida during medicinal leech therapy
E Ruppé1, A Cherkaoui2, N Wagner3
1Genomic Research Laboratory, Division of Infectious Diseases, Switzerland.
New Microbes and New Infections
|December 6, 2017
Abstract:
We report the selection in a 15-year-old boy of a multidrug-resistant, extended-spectrum β-lactamase (ESBL)-producing Aeromonas salmonicida after medicinal leech therapy that required an antibiotic prophylaxis based on piperacillin/tazobactam and cotrimoxazole. Whole genome sequencing of the strain indeed revealed 13 antibiotic resistance genes, including the ESBL CTX-M-3 and the unusual β-lactamase SCO-1.
