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Objective and subjective scar aesthetics with topical Manuka honey post-thyroidectomy: A randomized control study
Andrew Thamboo1, Graeme Mulholland1, Kathleen Matthews1
1Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, 801 Welch Road, Stanford, CA 94305, USA.
World Journal of Otorhinolaryngology - Head and Neck Surgery
|December 6, 2017
Summary
Manuka honey, known for wound healing, did not significantly improve scar appearance in this study. Researchers found no difference in scar quality between Manuka honey and standard treatment groups.
Area of Science:
- Dermatology
- Wound Healing Research
- Regenerative Medicine
Background:
- Leptospermum Honey (Manuka honey) exhibits antibacterial and anti-inflammatory properties, suggesting potential benefits for wound healing.
- Its efficacy in improving acute and chronic wound healing is well-documented.
Purpose of the Study:
- To investigate whether Manuka honey application reduces scar formation.
- To determine if Manuka honey results in cosmetically superior scars compared to standard treatment.
Main Methods:
- A prospective, single-blinded, randomized controlled trial was conducted.
- Patients received an 8 cm incision, with one group applying Manuka honey topically for 4 weeks post-surgery.
- Scar assessment utilized the Patient and Observer Scar Assessment Scale (POSAS) at 4 and 8 weeks.
Main Results:
- Twenty-one patients completed the study (9 in the honey group, 12 in the standard treatment group).
- No statistically significant differences were observed in patient or observer scar assessments between the groups at 4 and 8 weeks postoperatively.
Conclusions:
- Despite its known properties, Manuka honey did not demonstrate a significant effect on scar appearance in this trial.
- Further research may be needed to explore potential mechanisms or alternative applications for scar management.
