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Gallbladder Mucocele: Variables Associated with Outcome and the Utility of Ultrasonography to Identify Gallbladder
J A Jaffey1, A Graham1, E VanEerde2
1Department of Veterinary Medicine and Surgery, Veterinary Health Center, University of Missouri, Columbia, MO.
Journal of Veterinary Internal Medicine
|December 6, 2017
Summary
Gallbladder mucocele (GBM) in dogs significantly increases mortality risk when accompanied by gallbladder rupture and bile peritonitis. Ultrasonography shows low sensitivity for detecting rupture, highlighting the need for careful clinical assessment.
Area of Science:
- Veterinary Medicine
- Canine Surgery
- Diagnostic Imaging
Background:
- Gallbladder mucocele (GBM) is an emerging extrahepatic biliary disease in dogs.
- Diagnosis and management of GBM are critical for canine health.
- Understanding risk factors for GBM complications is essential.
Purpose of the Study:
- To investigate gallbladder mucocele (GBM) cases in dogs.
- Identify variables associated with survival in dogs with GBM.
- Evaluate the diagnostic performance of ultrasonography for gallbladder rupture.
Main Methods:
- Retrospective study of 219 client-owned dogs diagnosed with GBM.
- Data collected from 6 academic veterinary hospitals (2007-2016).
- Analysis included surgical and histopathologic findings, and ultrasonographic results.
Main Results:
- Dogs with GBM and gallbladder rupture with bile peritonitis were 2.7 times more likely to die.
- No significant association found between survival and positive bacterial cultures or antibiotic use.
- Ultrasonography demonstrated 56.1% sensitivity and 91.7% specificity for gallbladder rupture.
Conclusions:
- Gallbladder rupture and bile peritonitis significantly increase mortality risk in dogs with GBM.
- Abdominal ultrasonography has limited sensitivity for detecting gallbladder rupture.
- Early recognition and management of GBM complications are crucial for improving outcomes.
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