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The applications of regenerative medicine in sinus lift procedures: A systematic review
Francisco Correia1, Daniel Humberto Pozza2, Sónia Gouveia3
1Department of Oral Surgery and Periodontology, Faculty of Dental Medicine, University of Porto, Porto, Portugal.
Background:
Findings in regenerative medicine applied to the sinus lift procedures.
Purpose:
Evaluate the effectiveness of regenerative medicine in sinus lift.
Materials And Methods:
An extensive search for manuscripts were performed by using different combinations of keywords and MeSH terms (Pub-med; Embase; Scopus; Web of Science Core Collection; Medline; Current Contents Connect; Derwent Innovations Index; Scielo Citation Index; Cochrane library). The full text selected articles are written in English, Portuguese, Spanish, Italian, German, or French, and published until 28 of November 2016. Inclusion criteria were: implant osteointegration, radiographic, histologic, and/or histomorphometric analysis, clinical studies in humans using of regenerative medicine. This systematic review was performed by selecting only randomized controlled clinical trials and controlled clinical trials.
Results:
Eighteen published studies (11 CT and 7 RCT) were considered eligible for inclusion in the present systematic review. These studies demonstrated considerable variation of biomaterial and cell technics used, study design, sinus lift technic, outcomes, follow-up, and results.
Conclusion:
Only few studies have demonstrated potential of regenerative medicine in sinus lift; further randomized clinical trials are needed to achieve more accurate results.
