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Sexually Transmitted Infections

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Updated: Feb 17, 2026

Quantitative Examination of Antibiotic Susceptibility of Neisseria gonorrhoeae Aggregates Using ATP-utilization Commercial Assays and Live/Dead Staining
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Gonorrhea.

H Bradford Hawley

    Postgraduate Medicine
    |December 6, 2017
    PubMed
    Summary

    Gonorrhea is increasing in adolescents, especially Black teenagers, due to rising sexual activity, drug abuse, and antibiotic resistance. New single-dose oral antibiotic treatments offer improved management for this growing public health concern.

    Area of Science:

    • Public Health
    • Infectious Diseases
    • Adolescent Health

    Background:

    • Gonorrhea incidence is rising among adolescents, particularly Black teenagers, despite an overall decline in cases.
    • Factors contributing to this trend include increased sexual activity, substance abuse, and growing antibiotic resistance in Neisseria gonorrhoeae.
    • The changing epidemiology necessitates updated prevention, detection, and treatment strategies.

    Purpose of the Study:

    • To review the current epidemiology of gonorrhea in adolescents.
    • To discuss improvements in the prevention and detection of gonorrhea.
    • To introduce novel single-dose oral antibiotic treatments for gonorrhea.

    Main Methods:

    • Review of epidemiological data on gonorrhea trends in adolescents.

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  • Analysis of factors influencing disease transmission and resistance patterns.
  • Evaluation of emerging treatment options, including oral antibiotics.

    • Main Results:

    • Gonorrhea rates are disproportionately high in adolescent populations, especially among Black teenagers.
    • Antibiotic resistance is a significant challenge, complicating treatment efficacy.
    • New single-dose oral antibiotic regimens show promise for effective gonorrhea management.

    Conclusions:

    • Urgent public health interventions are needed to address the rise of gonorrhea in adolescents.
    • Enhanced prevention and early detection are critical to curb transmission rates.
    • Novel oral antibiotic treatments represent a significant advancement in managing this increasingly resistant infection.