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Studies on correlations between chloroquine-induced tissue damage and serum enzyme changes in the rat
E O Ngaha1, M A Akanji, M A Madusolumuo
1Department of Biochemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
Abstract:
The administration of chloroquine to rats resulted in a significant elevation of serum enzymes and a corresponding decrease of these enzymes in the tissues. The changes in serum and kidney enzymes were most marked, thus indicating a primary renal dysfunction.