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Updated: Feb 17, 2026
Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
Published on: August 20, 2021
Draft genome of the emerging pathogen, Kocuria marina, isolated from a wild urban rat
Shih Keng Loong1, Kim-Kee Tan1,2, Nurhafiza Zainal1,2
1University of Malaya, Faculty of Medicine, Tropical Infectious Diseases Research & Education Centre, Kuala Lumpur, Malaysia.
Abstract:
Kocuria marina has recently emerged as a cause for catheter-related bloodstream infections in patients with underlying health complications. One K. marina strain was recently isolated from the lung tissues of a wild urban rat (Rattus rattus diardii) caught during rodent surveillance. Here, we present the draft genome of the first K. marina animal isolate, K. marina TRE150902.
Insights
Kocuria marina causes bloodstream infections and was found in a wild rat. This study presents the genome of the first K. marina animal isolate, aiding in understanding its potential as a pathogen.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Kocuria marina is an emerging cause of catheter-related bloodstream infections, particularly in immunocompromised patients.
- Rodent surveillance programs can identify novel sources of potential human pathogens.
- Understanding the genetic makeup of K. marina is crucial for developing effective treatment and prevention strategies.
Purpose of the Study:
- To present the draft genome sequence of Kocuria marina TRE150902, the first reported animal isolate.
- To provide a genomic resource for future studies on K. marina pathogenesis and evolution.
Main Methods:
- Whole-genome sequencing of Kocuria marina TRE150902.
- Bioinformatic analysis of the draft genome.
Main Results:
- The draft genome sequence of Kocuria marina TRE150902 was successfully generated.
- This represents the first genome data available for an animal-derived K. marina strain.
Conclusions:
- The availability of the K. marina TRE150902 genome will facilitate research into its pathogenic potential.
- This genomic data may contribute to understanding the transmission dynamics and host adaptation of K. marina.
