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Single-Cell Analysis Using Hyperspectral Imaging Modalities.

Nishir Mehta1, Shahensha Shaik1, Ram Devireddy2

  • 1Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803.

Journal of Biomechanical Engineering
|December 7, 2017
PubMed
Summary
This summary is machine-generated.

Hyperspectral imaging (HSI) technology, initially used in satellite remote sensing, now enables detailed analysis of biological systems at micro- and nanoscales. This review explores HSI

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Area of Science:

  • Biomedical imaging
  • Optical spectroscopy
  • Remote sensing technology

Background:

  • Hyperspectral imaging (HSI) was pioneered by NASA for satellite remote sensing.
  • Applications expanded to mineral exploration, agriculture, water resources, and urban development.
  • Recent advancements enable HSI at micro- and nanometer scales for biological analysis.

Purpose of the Study:

  • To describe the working principle of HSI technology.
  • To illustrate HSI's potential to assist, substitute, and validate traditional imaging.
  • To highlight HSI applications in biological analysis and medical diagnostics, particularly single-cell analysis.

Main Methods:

  • Review of hyperspectral imaging principles.
  • Discussion of HSI applications in various scientific fields.
  • Focus on HSI for biological and medical imaging, including single-cell analysis.

Main Results:

  • HSI technology has evolved from satellite imaging to micro/nanoscale biological applications.
  • HSI offers a powerful tool for detailed analysis of biological systems.
  • The technology shows promise for medical diagnostics and single-cell studies.

Conclusions:

  • HSI is a versatile technology with a broad range of applications.
  • Advancements in HSI open new avenues for biological research and medical diagnostics.
  • Single-cell analysis using HSI is a rapidly developing field with significant potential.