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Updated: Feb 17, 2026

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
Published on: August 16, 2024
Mother and daughter with adolescent-onset severe frontal lobe dysfunction and epilepsy
Giordani Rodrigues Dos Passos1, Alonso Cuadrado Fernández1, Adriana Machado Vasques2
1Neurology Service, São Lucas Hospital, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre RS, Brazil.
Abstract:
Familial cases of early-onset prominent frontal lobe dysfunction associated with epilepsy have not been reported to date. We report a mother and her only daughter with incapacitating behavioral manifestations of frontal lobe dysfunction and epilepsy of variable severity. The possibility of a hitherto undescribed genetic condition is discussed.
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