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Progressive posterior cortical dysfunction.

Fábio Henrique de Gobbi Porto1, Gislaine Cristina Lopes Machado2, Lilian Schafirovits Morillo3

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Summary

Progressive posterior cortical dysfunction (PPCD) is a rare dementia affecting visual processing. This case highlights key symptoms and imaging findings for improved recognition of this neurological syndrome.

Keywords:
Balint’s syndromeposterior progressive cortical dysfunction syndromevisual agnosiavisuospatial dysfunction

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Area of Science:

  • Neuroscience
  • Neurology
  • Ophthalmology

Background:

  • Progressive posterior cortical dysfunction (PPCD) is a neurodegenerative syndrome impacting higher visual processing.
  • It affects dorsal and ventral visual pathways, leading to visuospatial and visual recognition deficits.

Observation:

  • A 67-year-old woman presented with progressive visual impairment.
  • Clinical findings included agraphia, alexia, hemispatial neglect, Balint's syndrome, and visual agnosia.

Findings:

  • Magnetic resonance imaging revealed bilateral parieto-occipital atrophy, more pronounced on the right.
  • The case illustrates a distinct presentation of dementia with significant visual disturbances.

Implications:

  • This case report aims to enhance the recognition of PPCD.
  • Understanding PPCD's visual manifestations is crucial for accurate diagnosis and management of dementia.