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Body mass index, cognitive deficit and depressive symptoms in high cardiovascular risk patients

Amanda Lucas da Costa1, Juliana Santos Varela1, Matheus Roriz Cruz2

  • 1Dementia Clinic, Neurology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre RS, Brazil.

Dementia & Neuropsychologia
|December 8, 2017
PubMed

Insights

Obesity is linked to cognitive impairment in high cardiovascular risk patients. This study found no association between obesity and depressive symptoms in this group.

Area of Science:

  • Cardiology
  • Neurology
  • Geriatrics

Background:

  • Obesity is a growing concern, particularly in individuals with high cardiovascular risk.
  • Cognitive impairment and depressive symptoms are prevalent in aging populations and can impact quality of life.

Purpose of the Study:

  • To investigate the relationship between obesity, cognitive impairment, and depressive symptoms.
  • To assess these associations in patients with high cardiovascular risk.

Main Methods:

  • A cohort of 93 patients aged 50+ with high cardiovascular risk was studied.
  • Cognitive function was assessed using the Mini Mental State Examination (MMSE).
  • Depressive symptoms were evaluated using the Geriatric Depression Scale (GDS-15).

Main Results:

  • Obese patients exhibited significantly lower MMSE scores compared to non-obese individuals (p=0.0012).
  • Each one-point increase in BMI above 30 correlated with a 27% higher likelihood of cognitive impairment.
  • Obese patients had a 31% greater chance of cognitive impairment than overweight subjects.

Conclusions:

  • A significant association exists between obesity and cognitive impairment in patients at high cardiovascular risk.
  • No significant association was found between obesity and depressive symptoms in this patient cohort.

Keywords:
cognitive impairmentdepressionobesity

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