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Pharmacologic Complement Inhibition in Clinical Transplantation

Vasishta S Tatapudi1, Robert A Montgomery2

  • 1Division of Nephrology, Department of Internal Medicine, NYU Langone Medical Center, New York, NY 10016 USA.

Current Transplantation Reports
|December 8, 2017
PubMed
Summary

Pharmacologic complement inhibition shows promise for preventing antibody-mediated rejection (AMR) in kidney transplant recipients. Complement blockade therapies are emerging as valuable tools for improving transplant outcomes, especially in highly sensitized patients.

Keywords:
Antibody-mediated rejectionC1 inhibitorComplementEculizumabKidney transplantation

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