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Optical Coherence Tomography: Basic Concepts and Applications in Neuroscience Research.

Mobin Ibne Mokbul1

  • 1Notre Dame College, Motijheel Circular Road, Arambagh, Motijheel, Dhaka 1000, Bangladesh.

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Optical coherence tomography (OCT) offers label-free, cross-sectional imaging for neuroscience research. This review highlights OCT

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Area of Science:

  • Neuroscience
  • Biomedical Imaging

Background:

  • Optical coherence tomography (OCT) is a micrometer-scale, label-free imaging modality utilizing tissue backscattering.
  • OCT has become widely adopted across various biomedical science fields, including neuroscience, since its invention in the 1990s.

Purpose of the Study:

  • To provide an overview of OCT applications in diverse neuroscience branches: neuroimaging, neurology, neurosurgery, neuropathology, and neuroembryology.
  • To summarize recent OCT applications in neuroscience research, compare findings, and discuss future opportunities and challenges.
  • To encourage broader adoption of OCT within the neuroscience community and establish a benchmark for future research.

Main Methods:

  • Review of existing literature on OCT applications in neuroscience.
  • Comparative analysis of recent OCT studies in various neuroscience subfields.
  • Discussion of current limitations and future potential of OCT in neuroscience.

Main Results:

  • OCT is a versatile tool with established applications in neuroimaging, neurology, neurosurgery, neuropathology, and neuroembryology.
  • The review details recent advancements and comparative data on OCT's utility across these neuroscience domains.
  • Despite limitations, OCT demonstrates significant value in both fundamental and clinical neuroscience research.

Conclusions:

  • Optical coherence tomography is a valuable imaging modality for basic and clinical neuroscience.
  • Further exploration and application of OCT in underutilized neuroscience branches are encouraged.
  • This review serves as a foundational resource for advancing OCT-based neuroscience research.