Related Experiment Video

Updated: Jan 3, 2026

Location, Dissection, and Analysis of the Murine Stellate Ganglion
07:50

Location, Dissection, and Analysis of the Murine Stellate Ganglion

Published on: December 22, 2020

12.4K

Cardiac Autonomic Neuropathy: Why Should Cardiologists Care about That?

Andrzej Bissinger1

  • 1Department of Interventional Cardiology and Arrhythmias, Medical University of Lodz, Lodz, Poland.

Journal of Diabetes Research
|December 8, 2017
PubMed

Insights

Early diagnosis of cardiac autonomic neuropathy (CAN) in diabetic patients is crucial for improving outcomes and reducing cardiac events. Simple heart rate variability methods allow preclinical CAN detection, recommending universal screening for all diabetic individuals.

Area of Science:

  • Cardiology
  • Diabetology
  • Neurology

Background:

  • Cardiac autonomic neuropathy (CAN) is a common, underdiagnosed diabetes complication.
  • CAN significantly impacts cardiac disorders, increasing morbidity, mortality, and sudden cardiac death risk.
  • It influences myocardial ischemia, infarction, hypertension, orthostatic hypotension, heart failure, and arrhythmias.

Purpose of the Study:

  • To review current evidence on CAN epidemiology, pathogenesis, cardiovascular effects, and diagnostics.
  • To highlight the importance of early CAN detection in diabetes management.

Main Methods:

  • Systematic review of recent literature on diabetic autonomic neuropathy and cardiac disorders.
  • Analysis of data on CAN's influence on the cardiovascular system.
  • Evaluation of diagnostic methods for CAN.

Main Results:

  • Early CAN diagnosis improves patient prognosis and reduces adverse cardiac events.
  • Heart rate variability methods offer simple, accessible, preclinical CAN diagnosis.
  • All diabetic patients should be screened for CAN per the Toronto Consensus Panel.

Conclusions:

  • Early diagnosis and screening for CAN are vital in diabetes care.
  • Heart rate variability and ECG-based methods are key diagnostic tools.
  • Collaborative efforts between diabetologists and cardiologists are essential for CAN diagnosis and management.
Abstract

More Related Videos

Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System06:40

Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System

Published on: May 22, 2018

11.1K
Quantitative Autonomic Testing11:40

Quantitative Autonomic Testing

Published on: July 19, 2011

58.4K

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
329
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
287
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
633
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
827
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
1.4K
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.6K