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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
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Acute Kidney Injury V: Interprofessional Care01:20

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Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
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Managing diabetic kidney disease.

Sagen Zac-Varghese1, Peter Winocour1

  • 1QE2 Hospital Howlands Welwyn Garden City, Welwyn GC AL7 4HQ, UK.

British Medical Bulletin
|December 8, 2017
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Summary
This summary is machine-generated.

Managing diabetic kidney disease (DKD) requires early diagnosis and controlling multiple risk factors like blood sugar and blood pressure. Novel medications show promise in reducing cardiovascular disease and DKD progression.

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Area of Science:

  • Nephrology
  • Endocrinology
  • Cardiology

Background:

  • Diabetes mellitus (DM) is the primary cause of chronic kidney disease (CKD).
  • Diabetic kidney disease (DKD) management is complex, involving multiple risk factors.
  • Increasing prevalence of DKD strains healthcare services.

Purpose of the Study:

  • To review essential management pillars for diabetic kidney disease (DKD).
  • To highlight areas of agreement and controversy in DKD care.
  • To identify emerging strategies and novel therapies for DKD.

Main Methods:

  • Literature search of PubMed using terms: diabetic nephropathy, diabetic kidney disease, diabetes and chronic kidney disease.
  • Inclusion of clinical guidelines from NICE, ABCD, JBS, and KDIGO.
  • Synthesis of evidence on risk factor management and novel treatments.

Main Results:

  • Key management strategies include early diagnosis, improved glycaemic control, hypertension treatment, metabolic bone disease management, and dyslipidaemia control.
  • Multiple risk factor reduction is crucial for preventing and managing DKD.
  • Novel anti-hyperglycaemic agents (SGLT2 inhibitors, GLP-1 RAs) reduce cardiovascular disease and DKD.
  • Disagreement exists regarding individualized glycaemic targets for DKD patients.

Conclusions:

  • Comprehensive management of DKD involves addressing glycaemic control, hypertension, dyslipidaemia, and other cardiovascular risk factors.
  • Novel anti-hyperglycaemic agents offer significant benefits for cardiovascular and renal outcomes.
  • Innovative management approaches, including technology solutions, are needed to meet the growing demand for DKD care.