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Updated: Feb 17, 2026

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria
Published on: October 4, 2024
GO-AgCl/Ag nanocomposites with enhanced visible light-driven catalytic properties for antibacterial and
Xinhuan Wang1, Qiusen Han2, Ning Yu3
1Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center of Excellence for Nanoscience, National Center for Nanoscience and Technology, UCAS, Beijing 100190, China.
Abstract:
Nanomaterials with visible light-driven photocatalytic activity have attracted much attention due to their excellent abilities in degradation of various organic pollutants as well as inactivating bacteria. Herein, graphene oxide (GO) enwrapped silver chloride/silver (AgCl/Ag) nanocomposites with high visible light absorption were designed and fabricated as efficient antibacterial agents. AgCl NPs were synthesized in the presence of GO first and Ag NPs were coated on AgCl surface by heat reduction to form GO-AgCl/Ag nanocomposites. The as prepared nanocomposites revealed improved stability, higher absorption properties in the visible light region. The enhanced antibacterial activity was observed by quantification of colony forming units (CFU) and morphological changes of bacteria. The antibacterial mechanism of GO-AgCl/Ag was also investigated by evaluating membrane permeability and ROS level. Moreover, GO-AgCl/Ag composites can eliminate bacterial biofilms more efficiently under visible light irradiation. Our results provide new insights into the design of new multifunctional systems for antibacterial applications.
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