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Lead Exposure and Oxidative Stress in Coal Miners
Zlatko Zimet1, Marjan Bilban2, Teja Fabjan3
1National Institute of Public Health, Trubarjeva 2, 1000 Ljubljana, Slovenia.
Abstract:
We aimed to investigate the short-term correlation between blood lead levels and oxidative stress generation in coal miners. The study involved 94 male coal miners from the Velenje Coal mine, arranged into four groups: three groups according to the number of consecutive working days, and a fourth control group. Miners who worked for three consecutive days had higher blood levels of lead and 8-isoprostane than the control group (P < 0.001). Correlation between lead and 8-isoprostane was of medium strength (r = 0.512, P < 0.001). Short-term lead environmental exposure can potentially harmful and should be considered when formulating improvements in working processes.
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