Related Experiment Video
Updated: Feb 17, 2026

Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo
Published on: July 13, 2015
Ciliary body location in eyes with and without primary congenital glaucoma
Ghadah Al Nosair1, Rajiv Khandekar1, Mohammed Al-Shamrani1
1King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Insights
Children with primary congenital glaucoma (PCG) have a greater ciliary body distance (CBD) from the limbus compared to healthy eyes. This finding in PCG eyes could improve surgical planning for congenital glaucoma.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Glaucoma Research
Background:
- Primary congenital glaucoma (PCG) is a serious condition affecting infants.
- Understanding the anatomical differences in PCG is crucial for effective treatment.
Purpose of the Study:
- To compare the ciliary body distance (CBD) in children with and without primary congenital glaucoma (PCG).
- To investigate the correlation between CBD and ocular parameters in PCG.
Main Methods:
- A cross-sectional study involving Saudi children under 5 years old.
- Ciliary body distance (CBD) measured using calipers and transillumination.
- Comparison of CBD between PCG and control groups, correlated with axial length, corneal thickness, and diameter.
Main Results:
- Mean CBD was significantly greater in the PCG group (1.6 mm) than in the control group (1.3 mm).
- CBD showed greater variability across quadrants in PCG eyes.
- CBD positively correlated with axial length, corneal thickness, and corneal diameter in PCG eyes.
Conclusions:
- Ciliary body distance from the limbus is increased in PCG eyes.
- The anatomical variations in CBD in PCG may inform surgical strategies.
- This knowledge can aid in optimizing surgical interventions for congenital glaucoma.
Objective:
To compare the location of ciliary body (CB) in children with and without primary congenital glaucoma (PCG).
Methods:
In this cross-sectional study, we enrolled Saudi children who were less than 5 years old. CB distance (CBD) was measured and compared in eyes with PCG (PCG group) and without PCG (control group). CBD was measured with a caliper and defined as the distance between the edge of the corneoscleral limbus and the anterior edge of CB as delineated by transillumination. The difference in the CBD between groups was correlated with the axial length, corneal thickness, and corneal diameter.
Results:
CBD was measured in 15 eyes in the PCG and control groups. The mean CBD (1.6 ± 0.4 mm) in the PCG group was significantly greater than that in the control group (1.3 ± 0.3 mm) (p < 0.001). The mean difference in the CBD of 2 groups was 0.33 mm (95% CI 0.15-0.54). In PCG eyes, the CBD was farthest in the superior quadrant (1.7 mm) followed by inferior (1.6 mm), temporal (1.6 mm), and nasal (1.5 mm) quadrants. The variability in CBD between quadrants in PCG eyes was greater than that in the control group. CBD in the PCG group showed a significant correlation with increasing axial length (p = 0.05), corneal thickness (p < 0.001), and corneal diameter (p = 0.0002).
Conclusions:
The CBD from the limbus was greater in PCG eyes compared to the controls and varied significantly in different quadrants. The knowledge regarding the greater CBD and its variability in PCG eyes could enable better planning of surgical treatment in congenital glaucoma.
Related Concept Videos
Glaucoma: Overview
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Muscles of the Eye
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
Accessory Structures of the Eye
Microtubules in Signaling

