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Successfully implementing and embedding guidelines to improve the nutrition and growth of preterm infants in neonatal
Mark J Johnson1,2, Alison A Leaf1,2, Freya Pearson2
1National Institute for Health Research, Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.
Insights
A complex intervention improved nutritional care for preterm infants, leading to better protein intake and weight gain. Normalization Process Theory (NPT) facilitated the integration of evidence-based practices into routine neonatal intensive care.
Area of Science:
- Neonatal Medicine
- Healthcare Implementation Science
- Nutritional Science
Background:
- Improving nutritional support for preterm infants is critical for optimal growth and development.
- Translating evidence-based nutritional guidelines into routine clinical practice remains a challenge.
- The Normalization Process Theory (NPT) provides a framework for understanding and facilitating the integration of new practices into healthcare settings.
Purpose of the Study:
- To develop and implement a multifaceted intervention to enhance the nutritional care of preterm infants.
- To utilize NPT to guide the implementation process and embed new practices into standard care.
- To evaluate the impact of the intervention on guideline compliance, nutrient intake, and infant growth.
Main Methods:
- A prospective, before-and-after interventional study was conducted in a tertiary neonatal intensive care unit.
- The intervention involved phased implementation of improved nutrition solutions, a dedicated nutrition team, education, guidelines, and screening tools.
- Data on guideline compliance, NPT scores, nutrient intake, and growth were collected continuously, with bimonthly audits.
Main Results:
- Guideline compliance consistently exceeded 75%, peaking at 85%, and showed a significant positive correlation with NPT scores.
- Significant improvements in daily protein intake and weight gain were observed during the intervention phases compared to the control period.
- These improvements in nutritional status and growth were sustained post-implementation.
Conclusions:
- The complex intervention, guided by NPT, was successfully integrated into routine practice, achieving high guideline compliance.
- The study demonstrates that NPT is an effective framework for implementing and sustaining changes in clinical care.
- Evidence-based complex interventions can significantly improve both clinical practice and outcomes for preterm infants.
Objectives:
We aimed to improve the nutritional care of preterm infants by developing a complex (multifaceted) intervention intended to translate current evidence into practice. We used the sociological framework of Normalization Process Theory (NPT), to guide implementation in order to embed the new practices into routine care.
Design:
A prospective interventional study with a before and after methodology.
Participants:
Infants <30 weeks gestation or <1500 g at birth.
Setting:
Tertiary neonatal intensive care unit.
Interventions:
The intervention was introduced in phases: phase A (control period, January-August 2011); phase B (partial implementation; improved parenteral and enteral nutrition solutions, nutrition team, education, August-December 2011); phase C (full implementation; guidelines, screening tool, 'nurse champions', January-December 2012); phase D (postimplementation; January-June 2013). Bimonthly audits and staff NPT questionnaires were used to measure guideline compliance and 'normalisation', respectively. NPT Scores were used to guide implementation in real time. Data on nutrient intakes and growth were collected continuously.
Results:
There were 52, 36, 75 and 35 infants in phases A, B, C and D, respectively. Mean guideline compliance exceeded 75% throughout the intervention period, peaking at 85%. Guideline compliance and NPT scores both increased over time, (r=0.92 and 0.15, p<0.03 for both), with a significant linear association between the two (r=0.21, p<0.01). There were significant improvements in daily protein intake and weight gain between birth and discharge in phases B and Ccompared with phase A (p<0.01 for all), which were sustained into phase D.
Conclusions:
NPT and audit results suggest that the intervention was rapidly incorporated into practice, with high guideline compliance and accompanying improvements in protein intake and weight gain. NPT appears to offer an effective way of implementing new practices such that they lead to sustained changes in care. Complex interventions based on current evidence can improve both practice and clinical outcomes.
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