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Updated: Jan 20, 2026

A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
Published on: July 22, 2022
Heads up Descemet membrane endothelial keratoplasty performed using a 3D visualization system
Virgilio Galvis1,2,3, Ruben D Berrospi1,2, Juan D Arias1,2
1Centro Oftalmológico Virgilio Galvis, Floridablanca, Colombia.
This study reports the first use of a 3D augmented reality system for Descemet membrane endothelial keratoplasty (DMEK). The innovative visualization system facilitated a successful corneal transplant procedure with excellent graft adhesion and visual outcomes.
Area of Science:
- Ophthalmology
- Surgical Technology
- Corneal Surgery
Background:
- Descemet membrane endothelial keratoplasty (DMEK) is a surgical procedure to restore vision by replacing damaged inner corneal layers.
- Traditional DMEK relies on surgical microscopes with eyepiece visualization.
Observation:
- A 68-year-old female patient underwent DMEK using a novel 3D augmented reality visualization system.
- The surgeon viewed a digital screen instead of traditional microscope eyepieces during the procedure.
Findings:
- The DMEK procedure was uneventful.
- Post-surgery, the graft showed good position and adherence.
- Corneal clarity was achieved with uncorrected distance visual acuity of 20/50 at five weeks.
Implications:
- This marks the first reported case of DMEK utilizing a 3D augmented reality visualization system.
- The technology may offer advantages for corneal surgeons during critical endothelial grafting steps.
- This approach could potentially enhance precision and outcomes in corneal transplantation.
Related Concept Videos
12:36A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
06:07Direct Bioprinting of 3D Multicellular Breast Spheroids onto Endothelial Networks
05:20Growth of Human and Sheep Corneal Endothelial Cell Layers on Biomaterial Membranes
08:58Visualization of Germinosomes and the Inner Membrane in Bacillus subtilis Spores
10:46Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
04:11Laser-assisted Selective Ablation of Porcine Corneal Endothelial Cells: A Technique to Induce Focused Porcine Corneal Endothelial Injury for Ex Vivo Studies

