Related Experiment Video
Updated: Feb 17, 2026
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
32.6K
A Practical Approach to Severe Asthma in Children
Emily E Barsky1,2, Lauren M Giancola1, Sachin N Baxi3,2
11 Division of Respiratory Diseases and.
Annals of the American Thoracic Society
|December 9, 2017
Summary
Severe asthma in children is complex and requires a systematic approach. Early diagnosis and tailored management, including addressing environmental and comorbid factors, are key to improving outcomes.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
- Respiratory Medicine
Background:
- Severe asthma in children, though a small subgroup, disproportionately burdens healthcare resources and causes significant morbidity.
- This condition is heterogeneous, necessitating specialized, evidence-based evaluation and management strategies.
Purpose of the Study:
- To outline a step-wise approach for the diagnosis and management of severe pediatric asthma.
- To differentiate between difficult-to-treat asthma and severe, uncontrolled asthma requiring advanced therapies.
Main Methods:
- Confirming asthma diagnosis and excluding mimics.
- Assessing medication adherence, environmental exposures, psychosocial factors, and comorbidities in difficult-to-treat cases.
- Evaluating steroid responsiveness and inflammatory patterns for advanced treatment eligibility.
Main Results:
- Systematic evaluation and management of adherence, environmental triggers, and comorbidities can optimize control in many cases.
- A subset of patients remains poorly controlled, requiring assessment for advanced therapies.
Conclusions:
- A structured, multi-faceted approach is crucial for managing severe pediatric asthma.
- For refractory cases, personalized treatment strategies, including biologics, are essential based on individual patient characteristics and inflammatory profiles.
Related Concept Videos
01:30Asthma-IV: Diagnostic and Management
3.2K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.2K
01:30Asthma-IV: Nursing Management
3.9K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
First, in...
3.9K
01:20Asthma: Pathogenesis and Management
1.4K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.4K
01:23Inhaled Medications
845
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
845
01:29Asthma-I: Introduction
3.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.6K
01:24Asthma-III: Symptoms and Complications
3.4K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
3.4K