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Encoding Allostery in mTOR Signaling: The Structure of the Rag GTPase/Ragulator Complex
1Laboratoire de Biologie et Pharmacologie Appliquée, CNRS and Ecole Normale Supérieure Paris-Saclay, Cachan, France.
Molecular Cell
|December 9, 2017
Abstract:
In this issue of Molecular Cell, Su et al. (2017) describe the structure of the Rag/Ragulator complex, a key relay in nutrient sensing by mTOR. The structure sheds new light on how signals are conveyed from the lysosome to mTOR.
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