Clinical analysis of acute myocardial infarction caused by coronary embolism

Zhen-Yu Jiao1, Da-Peng Zhang1, Kun Xia1

  • 1The Heart Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.

Journal of Thoracic Disease
|December 10, 2017
PubMed

Insights

Acute myocardial infarction (AMI) from coronary artery embolism often stems from left heart issues like rheumatic heart disease or atrial fibrillation. Angiography typically reveals artery occlusion without significant atherosclerosis.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Diagnostic Imaging

Background:

  • Acute myocardial infarction (AMI) can be caused by coronary artery embolism, a condition distinct from typical atherosclerotic causes.
  • Investigating the specific clinical and angiographic characteristics of AMI due to embolism is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To elucidate the clinical presentations and angiographic findings in patients experiencing acute myocardial infarction (AMI) triggered by coronary artery embolism.

Main Methods:

  • Retrospective analysis of clinical data from five patients diagnosed with AMI secondary to coronary artery embolism.
  • Review of coronary angiography results to identify characteristic vascular changes.

Main Results:

  • Identified underlying causes including left atrial myxoma (1), non-valvular atrial fibrillation (1), rheumatic heart disease (3), and mitral mechanical valve prostheses (1).
  • Coronary angiography demonstrated occlusion of the infarct-related artery (IRA) in all five patients, attributed to embolism, with an absence of significant atherosclerotic lesions elsewhere in the coronary arteries.

Conclusions:

  • Coronary artery embolism leading to AMI commonly involves embolic material originating from the left heart chambers.
  • Rheumatic heart disease and atrial fibrillation are frequently identified as primary causes of coronary artery embolism.
  • Coronary angiography is essential for diagnosing embolism-induced IRA occlusion, which may present with visible embolic signs.
Abstract

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