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Updated: Feb 17, 2026
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Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
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[Fertility preservation in oncology]
Laure Chaput1, Anne-Sophie Grémeau1, Solène Vorilhon2
1CHU de Clermont-Ferrand, service de biologie et médecine de la reproduction, AMP-CECOS, site Estaing, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France.
Bulletin Du Cancer
|December 10, 2017
Summary
Cancer survivors can preserve fertility using various methods tailored to age and sex. Fertility preservation is crucial for patients undergoing gonadotoxic treatments, with options like ovarian cortex freezing or sperm cryopreservation available.
Area of Science:
- Reproductive Medicine
- Oncology
- Bioethics
Background:
- Cancer treatments can impair fertility, impacting patients' reproductive potential.
- Increased cancer survival rates necessitate proactive fertility preservation strategies.
- Gonadotoxic therapies pose a significant risk to reproductive health.
Purpose of the Study:
- To review current fertility preservation techniques for cancer patients.
- To highlight the importance of offering fertility preservation options.
- To discuss the indications and methods based on patient demographics and treatment.
Main Methods:
- Review of established and emerging fertility preservation techniques.
- Discussion of methods applicable to different age groups (prepubertal, pubertal, adult) and sexes.
- Consideration of emergency fertility preservation scenarios.
Main Results:
- Ovarian cortex cryopreservation is the sole option for prepubertal girls.
- Oocyte vitrification and in vitro maturation are options for pubertal and adult women.
- Testicular tissue cryopreservation is the primary method for prepubertal boys, while sperm cryopreservation is standard for adult males.
Conclusions:
- Fertility preservation is a critical component of cancer care, supported by French bioethics law.
- A multidisciplinary approach is essential for optimizing fertility preservation strategies.
- Various established and experimental techniques ensure reproductive potential can be maintained.
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