Related Experiment Video
Updated: Feb 17, 2026

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy
Published on: October 6, 2022
Assessment of Normal-Flow Aortic Stenosis: Delving Too Deep?
Caroline Bleakley1, Mark J Monaghan2
1From the Department of Cardiology, King's College Hospital, London, United Kingdom.
No abstract available in PubMed .
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Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.