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Updated: Feb 17, 2026

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
Published on: April 6, 2016
Novel In Vitro Cancer Models for Optimizing Anti-EGFR Therapies
Stefania Napolitano1, Fortunato Ciardiello2
1Dipartimento di Internistica Cinica e Sperimentale "F. Magrassi," Università degli Studi della Campania "Luigi Vanvitelli," Napoli, Italy.
Abstract:
Preclinical models, which are able to recapitulate the biology and pathology of the original individual cancer, are needed to better investigate mechanisms of response and resistance to anticancer therapies. In this respect, novel in vitro models for metastatic colorectal cancer could be of high value. Clin Cancer Res; 24(4); 727-9. ©2017 AACRSee related article by Luraghi et al., p. 807.
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