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Updated: Feb 17, 2026

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Published on: April 7, 2015
Necrotising pneumonia caused by non-PVL Staphylococcus aureus with 2-year follow-up
Bryn Hilton1, Aniket N Tavare2, Dean Creer3
1School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Abstract:
Necrotising pneumonia (NP) is a rare but life-threatening complication of pulmonary infection. It is characterised by progressive necrosis of lung parenchyma with cavitating foci evident upon radiological investigation. This article reports the case of a 52-year-old woman, immunocompetent healthcare professional presenting to Accident and Emergency with NP and Staphylococcus aureus septicaemia. The cavitating lesion was not identified on initial chest X-ray leading to a delay in antimicrobial optimisation. However, the patient went on to achieve a full symptomatic recovery in 1 month and complete radiological recovery at 2-year follow-up. Long-term prognosis for adult cases of NP currently remains undocumented. This case serves as the first piece of published evidence documenting full physiological and radiological recovery following appropriate treatment of NP in an immunocompetent adult patient.
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