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Updated: Feb 17, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

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Evolving treatment paradigms in sickle cell disease.

Ramasamy Jagadeeswaran1,2, Angela Rivers1,2

  • 1Department of Pediatrics, University of Illinois at Chicago, Chicago, IL; and.

Hematology. American Society of Hematology. Education Program
|December 10, 2017
PubMed
Summary

Sickle cell disease (SCD) involves red blood cell damage due to hemoglobin S polymerization. Increased reactive oxygen species (ROS) worsen SCD symptoms, and reducing ROS is a key therapeutic target.

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