Related Experiment Video
Updated: Dec 31, 2025

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
Published on: December 4, 2021
Coupling Fluxes, Enzymes, and Regulation in Genome-Scale Metabolic Models
1Department of Bioengineering and Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. pjens@illinois.edu.
Abstract:
Genome-scale models have expanded beyond their metabolic origins. Multiple modeling frameworks are required to combine metabolism with enzymatic networks, transcription, translation, and regulation. Mathematical programming offers a powerful set of tools for tackling these "multi-modality" models, although special attention must be paid to the connections between modeling types. This chapter reviews common methods for combining metabolic and discrete logical models into a single mathematical programming framework. Best practices, caveats, and recommendations are presented for the most commonly used software packages. Methods for troubleshooting large sets of logical rules are also discussed.
More Related Videos
12:47Workflow Based on the Combination of Isotopic Tracer Experiments to Investigate Microbial Metabolism of Multiple Nutrient Sources
Published on: January 22, 2018
07:00Visualization and Analysis of mRNA Molecules Using Fluorescence In Situ Hybridization in Saccharomyces cerevisiae
Published on: June 14, 2013
Related Concept Videos
Metabolism of Chemolithotrophs
Introduction to Metabolism
Operon Model
Coordination of Gene Expression Processes in Bacteria
Regulation of Metabolism
Coupled Reactions
Energy in adenosine triphosphate or ATP molecules is easily accessible to do work. ATP powers the majority of energy-requiring cellular reactions....