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Children with atopic dermatitis may have unacknowledged contact allergies contributing to their skin symptoms

A B Simonsen1,2, J D Johansen2, M Deleuran1

  • 1Department of Dermatology and Venereology, Aarhus University Hospital, Aarhus, Denmark.

Journal of the European Academy of Dermatology and Venereology : JEADV
|December 10, 2017
PubMed

Insights

Children with atopic dermatitis (AD) have a higher risk of developing contact allergies, particularly to metals and skincare ingredients. Patch testing is crucial for identifying these unacknowledged allergies that can worsen skin symptoms.

Area of Science:

  • Dermatology
  • Allergology
  • Pediatrics

Background:

  • Atopic dermatitis (AD) in children may increase susceptibility to contact allergies due to a compromised skin barrier.
  • Previous studies on the link between atopic dermatitis and contact allergy in children have yielded conflicting results.
  • There is a recognized risk of underdiagnosing contact allergies in children with atopic dermatitis.

Purpose of the Study:

  • To investigate the prevalence of contact allergy in Danish children diagnosed with atopic dermatitis.
  • To explore how unrecognized allergies contribute to or exacerbate skin symptoms in children with atopic dermatitis.

Main Methods:

  • A cross-sectional study was conducted involving 100 children and adolescents aged 5-17 years with atopic dermatitis.
  • Participants underwent patch testing using a standardized pediatric series of 31 allergens.

Main Results:

  • Thirty percent of children with atopic dermatitis showed at least one positive patch test reaction.
  • Seventeen percent had a relevant contact allergy contributing to their current skin condition.
  • The likelihood of contact allergy was significantly associated with the severity of atopic dermatitis.
  • Metals and ingredients found in topical skincare products were the most common sensitizers.

Conclusions:

  • Patch testing serves as a valuable screening tool for managing children with atopic dermatitis, aiding in the detection of unacknowledged contact allergies.
  • Children with atopic dermatitis appear to have an elevated risk of sensitization to specific allergens, including metals and components of skincare products.
Abstract

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