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Updated: Feb 17, 2026
Spatial Measurements of Perfusion, Interstitial Fluid Pressure and Liposomes Accumulation in Solid Tumors
Published on: August 18, 2016
Characteristics of computed tomography perfusion parameters in non-small-cell-lung-cancer and its relationship to
Carmen Trinidad López1, Miguel Souto Bayarri2, Roque Oca Pernas3
1Department of Radiology, POVISA Hospital, Vigo, Spain.
Objectives:
To analyze computed tomography perfusion (CTP) parameters in NSCLC.
Materials And Methods:
Prospective study, 152 patients with NSCLC. CTP parameters were correlated with histology, stage, size and response to conventional chemotherapy/radiotherapy.
Results:
Neuroendocrine tumours presented higher BV (p 0.002). Negative correlation of PMB (p 0.003) and positive of MTT (p 0.046) with T stage was found. BF showed negative correlation with size. No differences were found with the RECIST levels of response to chemotherapy/radiotherapy.
Conclusions:
CTP parameters were highly variable. Neuroendocrine tumours presented higher BV and PMB values. Perfusion parameters do not differ depending on the stage and do not predict response to treatment.
