Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

594
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
594
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

456
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
456
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

456
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
456
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

483
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
483
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

577
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
577
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

225
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
225

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular tension indicators reveal unexpectedly complex regulation of tension in live mouse organs.

Communications biology·2026
Same author

Empagliflozin Attenuates Cardiac Fibrosis by Suppressing Fibroblast-Mediated C-C Motif Chemokine Ligand 2 Expression.

Journal of the American Heart Association·2026
Same author

Correction: Vascular Endothelial Growth Factor Blockade Promotes the Transition From Compensatory Cardiac Hypertrophy to Failure in Response to Pressure Overload.

Hypertension (Dallas, Tex. : 1979)·2025
Same author

Plaque rupture and calcified nodules: major contributors to out-of-hospital cardiac arrest in acute myocardial infarction.

Cardiovascular intervention and therapeutics·2025
Same author

Evaluation of <sup>177</sup>Lu-Labeled Lipiodol as a Targeted Radionuclide Therapy for Hepatocellular Carcinoma in a Preclinical Xenograft Model.

Molecular imaging and biology·2025
Same author

Spatial organizations of heterochromatin underpin nuclear structural integrity of ventricular cardiomyocytes against mechanical stress.

Cell reports·2025

Related Experiment Video

Updated: Feb 17, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.9K

IgA Vasculitis with Simultaneous Cardiopulmonary Involvement.

Kazunori Bando1, Hirofumi Maeba1, Ichiro Shiojima1

  • 1Division of Cardiology, Department of Medicine II, Kansai Medical University, Japan.

Internal Medicine (Tokyo, Japan)
|December 12, 2017
PubMed
Summary

This study reports a rare case of adult IgA vasculitis presenting with severe cardiopulmonary symptoms. Prompt diagnosis and corticosteroid treatment led to significant symptom improvement in this unique presentation.

Keywords:
IgA vasculitiscardiac involvementpulmonary involvement

More Related Videos

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
06:59

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

620
Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
09:22

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

12.6K

Related Experiment Videos

Last Updated: Feb 17, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.9K
Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
06:59

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

620
Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
09:22

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

12.6K

Area of Science:

  • Nephrology
  • Rheumatology
  • Pulmonology

Background:

  • Adult IgA vasculitis, a systemic small-vessel vasculitis, commonly affects the kidneys and gastrointestinal tract.
  • Cardiopulmonary involvement is less common but can lead to severe manifestations.

Observation:

  • A 60-year-old male with comorbidities presented with hemoptysis, dyspnea, and leg edema.
  • Diagnostic workup included physical examination, laboratory tests (elevated IgA fibronectin complexes), skin biopsy (leukocytoclastic vasculitis), and immunofluorescence (IgA and C3 deposits).

Findings:

  • The patient was diagnosed with adult IgA vasculitis.
  • The presentation was characterized by significant cardiopulmonary involvement without renal or gastrointestinal compromise.
  • Skin biopsy confirmed leukocytoclastic vasculitis with characteristic IgA and C3 deposition.

Implications:

  • This case highlights the diverse clinical spectrum of adult IgA vasculitis.
  • Early recognition and management of atypical presentations are crucial for patient outcomes.
  • Corticosteroid therapy demonstrated efficacy in resolving cardiopulmonary manifestations.