Genotoxicity, Bioactivity and Clinical Properties of Calcium Silicate Based Sealers: A Literature Review
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Published on: November 9, 2014
Farnaz Jafari1, Sanaz Jafari2, Paria Etesamnia3
1Department of Endodontics, Dental School, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Abstract:
An ideal endodontic sealer should have many properties such as excellent seal after setting, dimensional stability, slow setting time to ensure sufficient working time, insolubility to tissue fluids, adequate adhesion with canal walls and biocompatibility. Genotoxicity is one of the important factors that influence biocompatibility of an endodontic sealer. This literature review was conducted to survey the genotoxicity, bioactivity and clinical perspectives of calcium silicate based sealers. We searched PubMed using appropriate MeSH keywords. Also a hand search was conducted in the related journals. Sixty eight articles were assessed finally. Genotoxicity and acute inflammation were high in calcium silicate based sealers. Both resin-based and calcium silicate based sealers caused perceptible tooth discoloration. There were controversies regarding the fracture resistance, apical patency and retreatability of different sealers. Clinical properties of calcium silicate-based sealers are also outlined.
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