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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
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Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
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Vulnerable plaques, more than meets the i.

Emile Mehanna1, J Dawn Abbott1

  • 1Division of Cardiology, Rhode Island Hospital, Brown Medical School, Providence, Rhode Island.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|December 12, 2017
PubMed
Summary

Intravascular ultrasound (IVUS) imaging helps identify acute coronary syndromes. Current limitations hinder adoption of IVUS algorithms for tissue characterization, but future developments promise improved vulnerable plaque identification and prognostication.

Area of Science:

  • Cardiovascular Imaging
  • Interventional Cardiology
  • Biomedical Engineering

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Background:

  • Intravascular imaging, particularly intravascular ultrasound (IVUS), is crucial for understanding acute coronary syndromes.
  • Tissue characterization using post-processing IVUS algorithms like IMAP-IVUS and VH-IVUS is vital for identifying vulnerable plaques.
  • Current limitations in IVUS technology impede widespread clinical adoption for routine plaque analysis.