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Survival prediction in pancreatic cancer patients with no distant metastasis: a large-scale population-based estimate
Ning Pu1, Yang Lv1, Guochao Zhao1
1Department of General Surgery, Zhongshan Hospital, Institute of General Surgery & Shanghai Medical College, Fudan University, Shanghai 200032, PR China.
Aim:
To identify the risk factors for overall survival (OS) of pancreatic ductal adenocarcinoma patients with no distant metastasis, and formulate a novel nomogram for prognostic prediction.
Patients & Methods:
Data were obtained from Surveillance, Epidemiology, and End Results database of pancreatic ductal adenocarcinoma patients with no distant metastasis as the primary cohort, and 127 patients at our institution were enrolled as the validation cohort. The prognostic nomogram integrating all independent risk factors for predicting OS was established to achieve superior discriminatory ability.
Results:
The constructed nomogram showed excellent performance and superior predictive accuracy for OS according to the concordance index and calibration curve.
Conclusion:
One more advanced and accurate predictive model will be obtained to assist in risk stratification via the constructed nomogram.
