Electrochemical Sensing of Hydrogen Peroxide Using Block Copolymer Templated Iron Oxide Nanopatterns

A new enzyme-free sensor based on iron oxide (Fe₃O₄) nanodots fabricated on an indium tin oxide (ITO) substrate via a block copolymer template was developed for highly sensitive and selective detection of hydrogen peroxide (H₂O₂). The self-assembly-based process described here for Fe₃O₄ formation is a simple, cost-effective, and reproducible process. The H₂O₂ response of the fabricated electrodes was linear from 2.5 × 10^-3 to 6.5 mM with a sensitivity of 191.6 μA mM^-1cm^-2 and a detection limit of 1.1 × 10^-3 mM. The electrocatalytic activity of Fe₃O₄ nanodots toward the electroreduction of H₂O₂ was described by cyclic voltammetric and amperometric techniques. The sensor described here has a strong anti-interference ability to a variety of common biological and inorganic substances.