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Septic Cardiomyopathy

Sarah J Beesley1,2, Gerhard Weber3, Todd Sarge4

  • 1Pulmonary Division, Department of Medicine, Intermountain Medical Center, Murray, UT.

Critical Care Medicine
|December 12, 2017
PubMed

Insights

Septic cardiomyopathy, a cardiac dysfunction in sepsis, requires further study for clear definitions and treatment impacts. Current management focuses on sepsis treatment and supportive care for cardiogenic shock.

Area of Science:

  • Critical Care Medicine
  • Cardiology
  • Pathophysiology

Background:

  • Sepsis frequently causes cardiac dysfunction, termed septic cardiomyopathy.
  • Definitions and clinical implications of septic cardiomyopathy remain unclear.
  • Understanding septic cardiomyopathy is crucial for adult intensive care unit (ICU) patients.

Purpose of the Study:

  • To review the pathophysiology, management, and clinical implications of septic cardiomyopathy in adult ICUs.
  • To synthesize current knowledge on septic cardiomyopathy for clinical application.

Main Methods:

  • Literature review of relevant articles using PubMed.
  • Inclusion criteria: English language, human adults with sepsis.

Main Results:

  • Competing definitions of septic cardiomyopathy complicate its understanding.
  • Cardiac dysfunction is common in sepsis, but its prognostic and therapeutic impact requires demonstration.
  • Treatment involves addressing underlying sepsis and managing cardiogenic shock.

Conclusions:

  • Septic cardiomyopathy significantly contributes to organ dysfunction in sepsis.
  • Guided treatment may improve prognosis, particularly with reduced cardiac index.
  • Further research is needed on short- and long-term outcomes.
Abstract

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