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Reversible and Sensitive Hg2+ Detection by a Cell-Permeable Ytterbium Complex
Guochen Bao1,2, Shuai Zha1, Zhenyu Liu3,4
1Department of Chemistry, Hong Kong Baptist University , Kowloon Tong, Hong Kong SAR, People's Republic of China.
Inorganic Chemistry
|December 12, 2017
Abstract:
A cell-permeable ytterbium complex shows reversible binding with Hg2+ in aqueous solution and in vitroby off-on visible and NIR emission. The fast response and 150 nM sensitivity of Hg2+ detection is based upon FRET and the lanthanide antenna effect. The reversible Hg2+ detection can be performed in vitro, and the binding mechanism is suggested by NMR employing the motif structure in a La complex and by DFT calculations.

