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Toxicity studies with quinine hydrochloride
J C Colley1, J A Edwards, R Heywood
1Huntingdon Research Centre, Cambs, U.K.
Toxicology
|February 1, 1989
Abstract:
Three-month studies in the rat, a rat embryo-toxicity study and a specific study to investigate ototoxicity were carried out with quinine hydrochloride. The results of these studies suggest an acceptable daily intake of 40 mg quinine hydrochloride for an adult. There were no indications of teratogenic effects and no indications of interference with auditory function in rats receiving up to 200 mg/kg.