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Updated: Feb 17, 2026

Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
Published on: August 5, 2014
Dynamic functional disturbances of brain network in seizure-related cognitive outcomes
Jialing Guo1, Qian Wu2, Charlie W Zhao3
1Department of Neurology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, China.
Abstract:
Epilepsy is a prevalent neurologic disorder affecting approximately 50 million people worldwide. Cognitive dysfunction induced by seizures is one of the severe comorbidities of epilepsy and epileptic syndrome, which has a negative impact on epileptic patients' quality of life. Several mechanisms may be associated with cognitive impairment in patients with epilepsy. Here, we review how the dynamic functional alterations of brain network influence seizure-related cognitive outcomes.
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