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Susceptibility of HLA-E*01:03 Allele Carriers to Develop Cytomegalovirus Replication After Living-Donor Kidney

Hana Guberina1, Fabiola da Silva Nardi2, Rafael Tomoya Michita2

  • 1Department of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Germany.

The Journal of Infectious Diseases
|December 12, 2017
PubMed

Cytomegalovirus (CMV) causes serious complications among solid organ transplant recipients. We report the positive correlation between the presence of the HLA-E*01:03 allele in living-donor kidney recipients and CMV reactivation during the first year after transplantation. Thus, HLA-E genotyping may help identify CMV replication-prone patients who require individualized patient-based CMV management.

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